The main goal of closed loop

Closed loop control


Deep brain electrical stimulation can be a successful therapy in Parkinson's disease, in depression, and in several other psychiatric diseases, especially in drug-resistant cases. Unfortunately, chronic, continuous stimulation is associated with multiple side effects. This could be alleviated by delivering the electrical perturbation only when it is necessary, using closed-loop stimulation. Such an approach is essential for epilepsy, where seizures occur very rarely but with serious consequences. In a rat model for epilepsy, Berényi et al. (p. 735) prevented seizures by transcranial electrical stimulation using a closed-loop system. Transcranial electrical stimulation was highly effective and reduced seizure duration, on average, by 60 %.

Abstract

Many neurological and psychiatric diseases are associated with clinically detectable, altered brain dynamics. The aberrant brain activity, in principle, can be restored through electrical stimulation. In epilepsies, abnormal patterns emerge intermittently, and therefore, a closed-loop feedback brain control that leaves other aspects of brain functions unaffected is desirable. Here, we demonstrate that seizure-triggered, feedback transcranial electrical stimulation (TES) can dramatically reduce spike-and-wave episodes in a rodent model of generalized epilepsy. Closed-loop TES can be an effective clinical tool to reduce pathological brain patterns in drug-resistant patients.



Share this article





Related Posts


Closed loop controller
Closed loop controller

Latest Posts
Access Control Systems London
Access Control…
Free Advice and Security Audit Audio…
Go!Control Wireless Security system
Go!Control Wireless…
The 2GIG Go!Control is a wireless self-contained…
Access Control Systems suppliers
Access Control…
Close * Indicates primary type Manufacturer:…
Video Access Control Systems
Video Access…
Over the last decade municipalities have…
Wind turbine control Systems
Wind turbine…
Wind turbine OEMs must push the performance…
Search
Featured posts
  • Closed loop controller
  • Closed loop control systems Examples
  • Types of closed loop control system
  • What is closed loop control?
  • Closed loop control system project
  • Closed loop control system definition
  • Closed loop control systems
  • Closed loop control system diagram
  • Closed loop control diagram
Copyright © 2019 l www.oliver-control.com. All rights reserved.